Xaleve Ibuprofen 400MG

  • Xaleve is the FIRST and ONLY ibuprofen injection for IV infusion in Pakistan. At Hudson Pharma, we manufacture Xaleve using the Blow-Fill-Seal technology, which is an advantaged filling process, as stated by the U.S. FDA.
  • Xaleve is a Non-Steroidal Anti-Inflammatory Drug (NSAID).
  • Each 4 mL ampoule contains 400mg of ibuprofen.
  • It is available in a pack of 10s medical-grade LDPE ampoules.
  • Xaleve is recommended to be administered as an IV infusion only and must be diluted before use.

Product Information

Indications

  • Management of mild to moderate and moderate to severe pain.
  • Reduction of fever.

Contraindications

  • Hypersensitivity to ibuprofen, aspirin or any other NSAID.
  • History of asthma, urticaria or Coronary Artery Bypass Graft (CABG) surgery.

Adverse Effects

  • Nausea
  • Flatulence
  • Vomiting
  • Headache
  • Dizziness
  • Infusion site pain.

Additional Information/ Precautions

  • Xaleve is for IV infusion ONLY. It should not be given as an IV bolus or IM injection.
  • Xaleve should be used with caution in patients with known cardiovascular (CV) disease or risk factors for CV disease, a history of peptic ulcer disease and/or GI bleeding, liver/renal disease.
  • Xaleve should be avoided in pregnant women starting at 30 weeks gestation.

Dosage

Pain Fever
Adults 400mg to 800mg as an IV infusion over 30 minutes
(min. 10 minutes*) every 6 hours as necessary.
Max. daily dose is 3,200mg. 		400mg as an IV infusion over 30 minutes (min. 10 minutes*), followed by 400mg every 4 to 6 hours or 100-200mg every 4 hours as necessary.
Max. daily dose is 3,200mg.
Paediatrics
(6 months to <12 years) 		10mg/kg as an IV infusion over 10 minutes up to a max. single dose of 400mg every 4 to 6 hours as necessary.
Max. daily dose is 40mg/kg or 2,400mg, whichever is less.
Paediatrics
(≥12 to 17 years)		 400mg as an IV infusion over 10 minutes every 4 to 6 hours as necessary.
Max. daily dose is 2,400mg.
ADMINISTRATION
100mg to 400mg dose Dilute 1mL to 4mL of Xaleve in at least 100mL of diluent.
800mg dose Dilute 8mL of Xaleve in at least 200mL of diluent.

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